Publications from the Kavran Lab
Cairns L, Tran T, Kavran JM. Structural insights into the regulation of Hippo signaling. (2017) ACS Chem. Biol. 12:601-610.
Publications as a Post-doctoral Fellow
Marold, JD, Kavran, JM, and Barrick, D. A naturally occurring repeat protein with high internal sequence identity defines a new class of TPR-like proteins. Structure. In press
Werner, R, Merz, H, Strom, T, Birnbaum, W, Marshall, L, Schroder, T, Reiz, B, Kavran, JM, and Hior, O. (2015) Unusual 46,XY Gonadal Dysgenesis due to a homozygous mutation in Desert Hedgehog (DHh) identified by exome-sequencing. J. Clin. Endocrin. Metab. 100: 1022-1029.
Guo, LT, Wang, YS, Nakamura, A, Eiler, D, Kavran, JM, Wong, M, Kiessling, LL, Steitz, TA, O’Donoghue, P, Soll, D. Polyspecific pyrrolysyl-tRNA synthetases from directed evolution. (2014) Proc. Natl. Acad. Sci. 111, 16724-16729.
Kavran, JM, Ward, MD, Oladosu, OO, Mulepati, S and Leahy, DJ. (2010) All mammalian Hedgehog proteins interact with cell adhesion molecule, down regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J. Biol. Chem. 283, 24584-90.
Qiu, C, Tarrant, MK, Boronina, T, Longo, PA, Kavran, JM, Cole, RN, Cole, PA, and Leahy, DJ. (2009) In vitro enzymatic characterization of near full length EGFR in activated and inhibited states. Biochemistry. 48, 6624-32.
Publications as a Graduate Student
Kavran, JM, Gundllapalli, S, O’Donoghue, P, Englert, M, Soll, D, and Steitz, TA. (2007) Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation. Proc. Natl. Acad. Sci. 104, 11268-11273.
Publications as an Undergraduate Student
Ferguson KM, Kavran JM, Sankaran VG, Fournier E, Isakoff SJ, Skolnik EY, and Lemmon MA. (2000) Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. Mol. Cell. 6, 373-384.
Kavran JM*, Klein DE*, Lee A, Falasca M, Isakoff SJ, Skolnik EY, and Lemmon MA. (1998) Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains. J. Biol. Chem. 273, 30497-30508. (*) both authors contributed equally